Studies have demonstrated that mangiferin promotes bone formation and inhibits ferroptosis in both in vivo models (osteoporotic mice, iron-overloaded mice) and in vitro models (osteoblast ferroptosis, iron-overloaded osteoblasts) (87)
Biotinylated Glutathione Labeling Biotin-conjugated glutathione reagentssuch as BioGSH (reduced form), BioGSSG (oxidized form), and BioGEE (a cell-permeable ethyl ester analog)can be synthesized in vitro and applied in both in vitro and in vivo settings
In addition to its role in nucleotide synthesis, PRPP also serves as an intermediate in NAD production 7
Jiang, W., Zhang, D., Bursac, N
Glutathione plays a vital role in detoxification, immune defense, cellular repair, and protection against oxidative stress